Pharma & Biotech

Accelerate Drug Development with AI That Knows Regulation

Bringing a drug to market costs $2.6B and takes 10-15 years. We build AI that automates regulatory writing, optimizes clinical trial operations, and turns pharmacovigilance from a cost center into a strategic advantage.

50%
Faster Regulatory Writing
28%
Reduced Trial Timelines
$4.2M
Avg. Annual Cost Savings
Industry Challenges

Why Drug Development Timelines Keep Growing

Increasing regulatory complexity, trial diversity requirements, and data volumes are stretching pharma R&D budgets beyond sustainability.

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Regulatory Writing Bottleneck

A single NDA submission can exceed 100,000 pages. Medical writers spend months on documents that follow predictable patterns.

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Patient Recruitment Failures

80% of clinical trials fail to meet enrollment timelines. Poor site selection and narrow eligibility criteria waste millions.

⚠️

Pharmacovigilance at Scale

Post-market safety monitoring generates millions of adverse event reports. Manual review cannot keep pace with global reporting requirements.

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Data Silos Across the Pipeline

Discovery, preclinical, clinical, and commercial data live in separate systems with no unified view of the molecule lifecycle.

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Global Regulatory Variation

FDA, EMA, PMDA, and NMPA each have different submission formats, timelines, and requirements for the same drug.

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Declining R&D Productivity

Cost per approved drug has doubled every 9 years since 1950. The industry needs fundamentally different approaches to innovation.

Ready to Cut Regulatory Timelines by 50%?

See how AI-powered regulatory writing and trial optimization can accelerate your pipeline.

Pharma Impact

What Mid-Size Pharma Companies Achieve

Results from biotech and pharma clients with Phase II-IV programs across multiple therapeutic areas.

50%
Faster Reg Writing
28%
Shorter Trial Timelines
3x
Faster Signal Detection
$4.2M
Annual Savings
Impact Metrics

Where Pharma Teams See ROI

Three areas driving the biggest time and cost savings across the drug development lifecycle.

50%
Regulatory Writing Speed
AI-drafted CSR sections and CTD modules reduce medical writer workload from months to weeks per submission.
$2.1M
Trial Cost Reduction
Optimized site selection and predictive enrollment models reduce screen failures and site underperformance.
3x
Safety Signal Speed
Automated adverse event processing and ML-powered signal detection identify risks months earlier than manual review.
Compliance & Regulations

GxP and Regulatory Compliance

Every AI tool is built for the stringent regulatory requirements of pharmaceutical development.

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21 CFR Part 11
Electronic signature support, complete audit trails, access controls, and system validation documentation per FDA requirements.
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ICH E6(R2) / GCP
Clinical trial workflows aligned with Good Clinical Practice guidelines including data integrity and source verification.
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EMA & Global Submissions
Support for eCTD format, EudraVigilance reporting, and multi-regional submission coordination across FDA, EMA, and PMDA.
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GAMP 5 Validation
Risk-based validation approach following GAMP 5 principles with IQ/OQ/PQ protocols and ongoing monitoring procedures.
Why OpenMalo

Why Pharma Teams Choose OpenMalo

We combine deep regulatory domain knowledge with production-grade AI engineering.

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Life Sciences Domain Expertise
Our team includes former regulatory affairs professionals and clinical data managers who understand GxP from the inside.
Validation-First Approach
Every AI model ships with GAMP 5 validation protocols, performance baselines, and change control procedures.
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Data Sovereignty Guaranteed
Deploy in your validated environment. We support on-premise, private cloud, and qualified cloud infrastructure.
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Global Regulatory Coverage
Experience supporting submissions to FDA, EMA, PMDA, NMPA, and Health Canada with region-specific formatting.
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Measurable Pipeline Impact
We define success in terms of days saved, cost reduced, and quality improved — not AI buzzwords.
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Flexible Engagement Models
From proof-of-concept on a single program to enterprise deployment. Scale at your pace.
Get Started

Get a Pharma AI Readiness Assessment

Tell us about your pipeline and we will identify where AI can have the biggest impact.

Free regulatory workflow analysis
Clinical operations AI opportunity mapping
GxP compliance compatibility review
ROI projection in 5 business days
CDA executed before any data sharing
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Featured Case Study

Pharma Success

Case Study

Biotech Cuts NDA Preparation Time by 50%

A mid-size biotech used AI regulatory writing to prepare their first NDA submission while simultaneously optimizing Phase III enrollment.

50%
Faster Reg Writing
28%
Shorter Enrollment
$4.2M
Annual Savings
The Challenge

The Problem

A rare disease biotech had one shot at NDA submission with limited regulatory headcount and a Phase III trial that was 6 months behind enrollment targets.

Three medical writers managing a 75,000-page NDA with a fixed PDUFA date
Phase III trial enrolled at 40% of target with 6 months remaining
Safety database contained 50,000+ adverse event reports requiring manual review
No standardized process for multi-regional submission adaptation

Our Approach: We deployed regulatory writing AI to auto-generate CSR sections and CTD modules from clinical datasets, built an enrollment prediction model that identified 12 high-performing backup sites, and automated adverse event intake processing to clear the safety review backlog.

Read Full Case Study
Client Stories

What Our Clients Say

The AI generated our first CSR draft in 3 days. Our team spent their time reviewing and refining instead of writing from scratch.

KM
Dr. Katherine Moss
VP Regulatory Affairs, Axion Therapeutics

We identified a safety signal 4 months earlier than our standard review cycle would have caught it. That changed our risk management plan.

RP
Raj Patel
Head of Pharmacovigilance, BioVance

Their enrollment model pinpointed which sites to activate and which to drop. We hit our recruitment target 2 months ahead of the revised plan.

CL
Christine Liu
Director Clinical Ops, Meridian Bio
FAQ

Frequently Asked Questions

Yes. Every AI model includes GAMP 5-aligned validation documentation, IQ/OQ/PQ protocols, performance specifications, and change control procedures. We support deployment into qualified GxP infrastructure.